Nipah Virus: What You Need to Know Before Travelling in Asia

Nipah virus particle

What is the Nipah virus, and how does it spread?

Nipah virus (NiV) is an RNA virus belonging to the genus Henipavirus. It was first identified in 1999 during an outbreak among pig farmers in Malaysia and Singapore, where it caused severe respiratory and neurological disease in pigs and humans1. Since then, the Nipah virus has caused sporadic outbreaks in Bangladesh and India, primarily associated with consuming raw date palm sap contaminated by fruit bats, the natural reservoir of the virus2. Nipah virus can also spread from person to person through close contact with infected secretions and excretions3.

Nipah virus infection can cause many symptoms, from asymptomatic to fatal encephalitis (brain inflammation). The incubation period (the time between exposure and onset of symptoms) is usually 5 to 14 days but can range from 3 to 60 days4. The initial symptoms may include fever, headache, muscle pain, vomiting, sore throat, and cough. Some patients may develop respiratory distress, confusion, seizures, and coma. The case fatality rate (the proportion of infected people who die) is estimated at 40% to 75%, depending on the outbreak and health care5.

Where is the current outbreak from?

The current Nipah virus outbreak originated in Kerala, a state in India. The first case, whose source of infection is unknown, had pneumonia and acute respiratory distress syndrome (ARDS) and was admitted to a hospital in late August 20231. He died a few days after admission1. The other five confirmed cases were close contacts of the first case, including two family members and communications at the hospital where the first case was treated and died. The second death occurred in an individual who accompanied another patient to the hospital where the first case was treated1. He died after presenting with symptoms of pneumonia1.

This is the sixth outbreak of the Nipah virus in India since 20011.

Countries of interest

Country Number of patients in current outbreak Number of patients in past outbreaks Number of deaths in current outbreak Number of deaths in past outbreaks Case fatality rate in current outbreak Case fatality rate in past outbreaks Screening measures
India 61 1912 21 1042 33.3%1 54.5%2 Temperature check and health questionnaire for travellers from Bangladesh and Kerala3
Bangladesh 144 2892 104 2022 71.4%4 69.9%2 Temperature check and health questionnaire for travellers from India3
Indonesia 056 056 056 056 N/A56 N/A56 Temperature check and health questionnaire for travellers arriving and departing from Bali7
Malaysia 08 2838 0 109 N/A 38.5% None since 1999
Singapore 0 11 0 1 0 9.1% None since 1999

No specific treatment, antiviral, or vaccine is available for Nipah virus infection in humans or animals1234. The only way to treat the disease is through supportive care, such as fluids, oxygen, and medications to control fever and seizures1234. However, some experimental treatments, such as monoclonal antibody therapies and remdesivir1, are currently under development and evaluation. These treatments have yet to be proven effective or safe for humans and are not widely available1. Therefore, prevention is the best strategy to avoid Nipah virus infection.

Which countries are currently screening for it?

The countries that are screening for Nipah virus outbreak in the present are:

  • Indonesia: All travellers arriving and departing from Bali must undergo a temperature check using an infrared thermometer and a health questionnaire123. Anyone who records a high temperature or has travelled from where the Nipah virus is present will be taken directly to the hospital for assessment123.
  • Bangladesh: Temperature check and health questionnaire for travellers from India4.
  • India: Temperature check and health questionnaire for travellers from Bangladesh and Kerala4.

Which countries are at risk?

The countries at risk for Nipah virus infection are those where the virus has been detected in bats or other animals or where outbreaks have occurred in humans in the past or present. These countries include:

  • Bangladesh123
  • India123
  • Malaysia43
  • Philippines43
  • Singapore43

These countries have reported Nipah virus outbreaks in humans and animals. They may have implemented health screenings and travel restrictions for travellers arriving and departing from their territories as a precautionary measure.

These countries may not have reported any cases of Nipah virus infection in humans or animals so far. Still, they should be vigilant and prepared for the possibility of an outbreak. Travellers to these countries should also know the risk factors and take preventive measures to protect themselves from Nipah virus infection.

Essential Travel Tips for Visiting Nipah Virus-Affected Countries

  • Avoid contact with sick animals. Nipah virus can be transmitted from animals such as bats and pigs to humans through their saliva, urine, feces, or blood. Therefore, you should avoid contact with sick or dead animals or their products. You should also avoid areas where bats are known to roost or feed. If you are bitten or scratched by an animal, wash the wound with soap and water immediately and seek medical attention as soon as possible.
  • Do not consume raw fruits or unpasteurized animal products. Nipah virus can also be transmitted through consumption of contaminated food or drinks. Therefore, you should avoid eating or drinking products that could be contaminated by bats or other animals, such as raw date palm sap (a popular drink in Bangladesh), raw fruits (especially those that have fallen on the ground), unpasteurized milk or cheese. You should also peel or wash fruits and vegetables before eating them.
  • Practice proper hand hygiene. Handwashing is one of the most effective ways to prevent the spread of germs. You should wash your hands with soap and water frequently, especially before eating or drinking, after using the toilet, after touching animals or their products, and after coughing or sneezing. You should also avoid touching your eyes, nose, or mouth with unwashed hands.
  • Avoid crowded or heavily populated areas. Nipah virus can also spread from person to person through close contact with infected secretions and excretions. Therefore, you should avoid crowded or heavily populated areas where you may come into contact with sick people or their body fluids. You should also avoid sharing utensils, cups, or bottles with others.

The World Health Organization (WHO) recommends the following measures to prevent Nipah virus infection6:

  • Practice handwashing regularly with soap and water
  • Avoid contact with sick bats or pigs
  • Avoid areas where bats are known to roost
  • Avoid eating or drinking products that could be contaminated by bats, such as raw date palm sap, natural fruit, or fruit that is found on the ground
  • Avoid contact with the blood or body fluids of any person known to be infected with NiV
  • Use standard infection control practices and proper barrier nursing techniques in health care settings where a patient has confirmed or suspected NiV infection

If you are travelling to Bali or any other region where the Nipah virus may be present, you should also:

  • Check the latest travel advice from your government or health authorities before departure
  • Monitor your health during and after your trip
  • Seek medical attention immediately if you develop any symptoms suggestive of NiV infection
  • Inform your healthcare provider about your travel history and any possible exposure to bats or pigs
  • Follow the instructions of the local health authorities regarding screening, quarantine, or isolation

Nipah virus is a severe disease that can threaten public health and animal welfare. However, being aware of the risk factors and taking preventive measures can reduce your chances of getting infected and enjoy your trip safely.

Nipah Virus and Air Travel

Nipah virus can pose a risk for air travel, as it can be transmitted from person to person through close contact with infected secretions and excretions. Therefore, measures have been taken by airlines and airports to prevent the spread of Nipah virus among passengers and staff. Here are some tips for safe air travel:

  • Check the airline’s policy on Nipah virus before booking your flight. Some airlines may have specific requirements or restrictions for travellers from or to countries where Nipah virus is present or have occurred in the past or present . For example, some airlines may require a negative RT-PCR test result for Nipah virus before boarding or after arrival. Some airlines may also cancel or reschedule flights to or from affected areas. You should check the airline’s policy on Nipah virus before booking your flight and follow their instructions accordingly.
  • Wear a mask and practice social distancing during your flight. To reduce the risk of exposure to Nipah virus or other respiratory infections during your flight, you should wear a mask that covers your nose and mouth and practice social distancing as much as possible. You should also avoid touching your eyes, nose, or mouth with unwashed hands and use hand sanitizer frequently.
  • Follow the airport’s screening procedures and health guidelines. When you arrive at or depart from an airport in a country where Nipah virus is present or have occurred in the past or present , you may be subject to screening procedures and health guidelines by the airport authorities. These may include temperature checks, health questionnaires, swab tests, quarantine orders, or isolation facilities. You should follow the airport’s screening procedures and health guidelines and cooperate with the airport staff.

What to Do in Case of Emergency

If you are travelling to a country where Nipah virus may be present or have occurred in the past or present , you should be prepared for any emergency situation that may arise. Here are some tips to help you:

  • Know the emergency numbers and contact information for local authorities. You should have a list of emergency numbers and contact information for local authorities, such as police, ambulance, fire brigade, hospital, embassy, or consulate. You should also have a list of emergency numbers and contact information for your travel insurance provider, family members, friends, or colleagues.
  • Seek medical help immediately if you experience symptoms of Nipah virus infection. If you develop any symptoms suggestive of Nipah virus infection, such as fever, headache, muscle pain, vomiting, sore throat, cough, respiratory distress, confusion, seizures, or coma, you should seek medical help immediately. You should inform your health care provider about your travel history and any possible exposure to bats or pigs. You should also follow the instructions of the local health authorities regarding screening, quarantine, or isolation.
  • Notify your travel insurance provider. If you have purchased comprehensive travel insurance that covers medical evacuation and repatriation in case of emergency, you should notify your travel insurance provider as soon as possible. You should provide them with your policy number, personal details, location, medical condition, and contact information. You should also follow their advice on how to proceed with your claim.

Conclusion

Nipah virus is a severe and often fatal disease that can be transmitted from animals such as bats and pigs to humans, and also from person to person. The virus has resulted in sporadic outbreaks primarily in Southeast Asia and the Indian Subcontinent. Prevention remains the best strategy against Nipah virus infection, given the absence of a specific treatment or vaccine. Countries at risk are implementing screening measures, and certain guidelines are provided for travelers to these areas. This includes avoiding contact with sick animals, practicing good hand hygiene, consuming only well-cooked food, and maintaining social distance. As the situation evolves, it is crucial to stay updated on the latest travel advisories and health guidelines from reputable sources.

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